INTECINCONICETUBAFacultad de Ingenieria

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Materials Engineering | Institute of Biomaterials

Biomaterials Group for Prosthesis

UBA Faculty of Engineering. Department of Physics.
Paseo Colón 850. (C1063ACV ) Ciudad Autónoma de Buenos Aires.
Phone: +54 11 4343 0092 extension: 214 / 133

Research Field

Biomaterials and Powder Metallurgy.

Bone substitutes and controlled porosity prosthetic components:
Development of synthesis processes of ceramic and metallic biocompatible materials.
Micrestructura studies, mechanical properties, biocompatibility (in vivo tests, absorption in the body, cytotoxicity, osseointegration).
Application to devices: bone substitutes and prostheses and orthopedic inserts custom.

Members

Direction:

Ozols, Andrés. PhD. Profesor Adjunto.

aozols@fi.uba.ar

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Fernández, Virginia. PhD. Ayudante Primera.

Grana, Daniel Rodolfo. PhD. Profesional Principal de CONICET.

Gregorutti, Ricardo. PhD.

Pagnola, Marcelo. PhD. Profesor Adjunto.

mpagnola@fi.uba.ar

Bernal, Teresa. M.S.

Rozenberg, Silvia Mirta. M.S. Profesora Adjunta.

srozen@fi.uba.ar

Alonso, Claudio.

Faig, Javier.

Fernández, Carlos.

López Ovenza, Manuel.

Luna, Gerardo. Técnico Electrónico (FIUBA).

Martínez, Cristian. Beca ANPCyT.

Work Description

The GBP is conducting a research project entitled Shaping metal fast as surgical prostheses, since early 2004. The overall objective of it is the molding of metal and ceramic prostheses to the extent of a patient, using the technique of gelcasting. Particular aim is both to control the use of the technique (which will bring it to the surface and structural conditions imposed by the application) as biological and preclinical validation of the procedures employed. The gelcasting was originally developed for the molding of ceramics and has been adapted by the GBP to metals. The process is based on the formulation of slips (dispersions of particles in solvents, organic monomers and polymers). These are cold cast in molds, where the polymerization proceeds. The raw parts are subjected to the pan and heat treatment cycle: elimination of solvents, pyrolysis of organic compounds and final sintering. To date, this technique has been applied to surgical stainless steel AISI 316 L, natural hydroxyapatite and other calcium phosphates.These powders are shaped in various forms: metal prosthetic components and bone, and simple geometry to be used only for bone repair. This process allows the control of density and porosity and surface finish of parts. The safety and efficacy of these materials and medical devices are being made through microstructural studies, mechanical testing and biological (biocompatibility and osseointegration) in accordance with ASTM and ISO standards and protocols for use of laboratory animals.
The success of the project will carry out preclinical studies necessary for the application of the technique for the manufacture of components necessary for bone and dental prostheses, orthopedics and traumatology, neurocirigía and maxillo-facial surgery.


External advisors and research partners
1. Marcelo Szriber, Mechanical Engineer, specialist in medical devices, Director of Micromed System, specializes in design and production of orthopedic prostheses.
2. Claudio Alonso, Traumatology, Medical Specialist for Orthopaedics and Traumatology Chief of Orthopedics and Traumatology of the Hospital de Clínicas "José de San Martín", teachers seconded from the Faculty of Medicine of the UBA.
3. Carlos F. Sancineto, Traumatology, Medical Specialist for Orthopaedics and Traumatology, Head of the Department of Orthopedics and Traumatology of the Hospital Italiano, a professor of the Faculty of Medicine of the UBA.
4. Carlos Maria Autorino, Traumatology, Medical Specialist for Orthopaedics and Traumatology Chief of Orthopedics and Traumatology Hospital Austral.